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Structure of 13682-18-3
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2-(3-Nitrophenyl)imidazole is a bench-stable heterocyclic compound featuring an electron-deficient imidazole core fused to a nitro-substituted phenyl ring. This structural combination enables direct integration into transition-metal-catalyzed coupling reactions, where the para-nitro group serves as a handle for further functionalization. The molecule exhibits enhanced solubility in polar organic solvents and demonstrates robust stability under standard handling conditions.
2-(3-Nitrophenyl)imidazole serves as a versatile building block in medicinal chemistry, enabling the construction of biologically active heterocyclic scaffolds. Its ortho-nitroaryl group facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions, while the imidazole core provides hydrogen-bonding capacity and metabolic stability. The compound exhibits bench stability and compatibility with standard purification methods, making it suitable for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: