2'-F-Bz-A

Name: 2'-F-Bz-A
Brand: ChemScene
Availability: InStock
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CAS No. 136834-20-3
Cat. No. CS-0132079
Purity≥97%
MDL No.MFCD22373350

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 136834-20-3

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Description

2'-F-Bz-A features a fluorinated benzyl group that enhances metabolic stability and lipophilicity in bioactive molecule design. This derivative integrates readily into nucleoside scaffolds, improving cellular uptake and target engagement under standard conditions.

Application

2'-F-Bz-A serves as a versatile building block in medicinal chemistry, enabling the incorporation of fluorinated aromatic motifs into bioactive molecules. Its stability under standard synthetic conditions and compatibility with common coupling reactions facilitate efficient integration into complex scaffolds. The 2'-fluorobenzyl group provides enhanced metabolic stability and modulates electronic properties, making it valuable for optimizing pharmacokinetic profiles in target-directed synthesis.

General Information

CAS No. 136834-20-3
Cat. No. CS-0132079
Purity ≥97%
MDL No. MFCD22373350
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₇H₁₆FN₅O₄
Molecular Weight 373.34
Synonym(s) N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine
SMILES O=C(C1=CC=CC=C1)NC2=C3N=CN([C@H]4[C@H](F)[C@H](O)[C@@H](CO)O4)C3=NC=N2

Computational Chemistry Data

TPSA 122.39
LogP 0.6673
H_Acceptors 8
H_Donors 3
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Life Science Nucleosides & Nucleotides TFA-modified nucleosides

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleobases and their Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleoside Analogs

Biochemistry Biochemicals and Reagents Nucleosides, Nucleotides, Oligonucleotides Nucleosides

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2'-F-Bz-A

CAS No. 136834-20-3

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