2-Chloro-5-fluoro-3-nitropyridine

Name: 2-Chloro-5-fluoro-3-nitropyridine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 136888-21-6
Cat. No. CS-W018687
Purity≥97%
MDL No.MFCD06659490

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-5-fluoro-3-nitropyridine|CS-W018687

Structure of 136888-21-6

Size

Price

Quantity

* Please select Quantity before adding items.

Description

2-Chloro-5-fluoro-3-nitropyridine features a trifunctional pyridine core with complementary electron-withdrawing groups enabling precise tuning of reactivity. The ortho-chloro and para-fluoro substituents facilitate palladium-catalyzed cross-coupling, while the meta-nitro group serves as a handle for selective reduction or nucleophilic displacement. This scaffold integrates readily into complex heterocyclic architectures under standard conditions.

Application

2-Chloro-5-fluoro-3-nitropyridine serves as a versatile heterocyclic building block for medicinal chemistry and agrochemical synthesis. Its orthogonal reactivity enables selective functionalization at the chloro, fluoro, or nitro positions via cross-coupling, nucleophilic substitution, or reduction protocols. The molecule exhibits good bench stability and facilitates efficient access to substituted pyridine scaffolds commonly found in pharmaceutical intermediates.

General Information

CAS No. 136888-21-6
Cat. No. CS-W018687
Purity ≥97%
MDL No. MFCD06659490
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₂ClFN₂O₂
Molecular Weight 176.53
Synonym(s) 2-cyanoethyl bis(1-methylethyl)amidochlorophosphite
SMILES ClC1=NC=C(C=C1[N+](=O)[O-])F

Computational Chemistry Data

TPSA 56.03
LogP 1.7823
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2-Chloro-5-fluoro-3-nitropyridine sigma2-Chloro-5-fluoro-3-nitropyridine manufacturer2-Chloro-5-fluoro-3-nitropyridine price2-Chloro-5-fluoro-3-nitropyridine structure2-Chloro-5-fluoro-3-nitropyridine SDSbuy 2-Chloro-5-fluoro-3-nitropyridine2-Chloro-5-fluoro-3-nitropyridine supplier2-Chloro-5-fluoro-3-nitropyridine uses2-Chloro-5-fluoro-3-nitropyridine molecular weightprice of 2-Chloro-5-fluoro-3-nitropyridine2-Chloro-5-fluoro-3-nitropyridine chemical name formula of 2-Chloro-5-fluoro-3-nitropyridine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-5-fluoro-3-nitropyridine

CAS No. 136888-21-6

Recommended Products