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Structure of 1370534-60-3
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2-Chloro-4-fluoro-5-iodopyridine is a halogenated pyridine derivative featuring strategically positioned chlorine, fluorine, and iodine substituents. This combination enables efficient cross-coupling reactions in late-stage functionalization. The molecule exhibits excellent stability under standard conditions and serves as a key intermediate in the synthesis of bioactive heterocycles.
2-Chloro-4-fluoro-5-iodopyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The strategically positioned chloro, fluoro, and iodo substituents allow for sequential functionalization, with the iodide site readily participating in Suzuki, Stille, or Negishi couplings. Bench-stable and compatible with standard purification protocols, it facilitates efficient access to complex heterocyclic scaffolds common in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: