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Structure of 13722-96-8
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2,4-Dihydroxy-5-nitrobenzoic acid features a conjugated aromatic core bearing two phenolic hydroxyls and a strongly electron-withdrawing nitro group. This arrangement imparts enhanced acidity and redox activity, enabling efficient coupling in synthetic transformations. The molecule demonstrates robust stability under standard conditions, facilitating direct use in derivatization workflows without preactivation.
2,4-Dihydroxy-5-nitrobenzoic acid serves as a versatile building block for bioactive heterocycles and pharmaceutical intermediates. Its ortho-dihydroxy and nitro groups enable selective metal-catalyzed coupling reactions and facilitate efficient derivatization via esterification or amidation. The molecule exhibits good bench stability and is readily purified by recrystallization, supporting its use in multi-step synthesis workflows requiring functional group compatibility.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501
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Lot numbers can be found on the outside label of a product: