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Structure of 1375108-41-0
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7-Bromo-3-methylquinoline is a halogenated quinoline derivative featuring a bromine atom at the 7-position and a methyl group at the 3-position. This electron-deficient heterocycle serves as a key scaffold in synthetic medicinal chemistry, enabling efficient coupling reactions via palladium catalysis. The strategic substitution pattern enhances metabolic stability and modulates lipophilicity for drug discovery applications.
7-Bromo-3-methylquinoline serves as a versatile building block in medicinal chemistry and catalytic cross-coupling reactions. The bromine at the C7 position enables reliable Suzuki, Stille, or Negishi coupling for C–C bond formation, while the methyl group at C3 provides a site for further functionalization. Its stability under standard reaction conditions and compatibility with diverse catalyst systems make it a practical choice for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: