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Structure of 137736-06-2
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4-(4-Fluorophenoxy)benzaldehyde features a fluorinated aromatic ether linkage fused to an aldehyde-bearing benzene ring. This electron-deficient aldehyde integrates readily into Suzuki and Ullmann coupling reactions, offering high functional group tolerance. The para-fluorine substituent enhances metabolic stability and facilitates downstream derivatization in medicinal chemistry applications.
4-(4-Fluorophenoxy)benzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient construction of biaryl and heterocyclic scaffolds. Its aldehyde functionality facilitates nucleophilic addition, reductive amination, and condensation reactions with high functional group tolerance. The fluorophenoxy moiety enhances metabolic stability and modulates electronic properties, making it valuable for optimizing pharmacokinetic profiles in API development. Bench-stable and readily purified by recrystallization, it supports scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H318-H411
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Precautionary Statements : P264-P270-P273-P280-P330-P391-P501
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Lot numbers can be found on the outside label of a product: