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Structure of 13781-53-8
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2-(Thiophen-3-yl)acetonitrile features a thiophene ring directly linked to an acetonitrile group, delivering a robust electron-deficient heteroaromatic scaffold. This configuration enables direct integration into cross-coupling reactions and facilitates the synthesis of functionalized pharmaceutical intermediates with enhanced solubility and stability under standard conditions.
2-(Thiophen-3-yl)acetonitrile serves as a versatile building block in medicinal and synthetic chemistry, enabling efficient access to thiophene-containing heterocycles. Its nitrile group facilitates nucleophilic addition, reduction, or cyclization reactions, while the thiophene moiety provides structural rigidity and π-conjugation. The compound exhibits good bench stability, ease of purification, and compatibility with standard coupling and functionalization protocols, making it well-suited for modular synthesis of bioactive scaffolds and API intermediates.
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3276
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: