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Structure of 138-36-3
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4-Bromobenzenesulfonic acid features a bromine substituent at the para position relative to a sulfonic acid group, creating a strongly electron-withdrawing functionality. This configuration enhances its reactivity in electrophilic substitution and facilitates coupling reactions under mild conditions. The compound exhibits high solubility in polar solvents and stability under standard bench handling, making it well-suited for synthetic applications in pharmaceutical intermediates and functional materials.
4-Bromobenzenesulfonic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient sulfonation-directed functionalization and transition-metal-catalyzed coupling reactions. Its bromo group facilitates palladium-catalyzed cross-couplings, while the sulfonic acid moiety provides water solubility and serves as a directing group or temporary handle for further derivatization. The compound exhibits excellent bench stability and is compatible with a range of reaction conditions, making it a practical choice for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: