7-Chloroimidazo[1,2-b]pyridazine

Name: 7-Chloroimidazo[1,2-b]pyridazine
Brand: ChemScene
Availability: InStock
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CAS No. 1383481-11-5
Cat. No. CS-W006906
Purity≥98%
MDL No.MFCD24387377

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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7-Chloroimidazo[1,2-b]pyridazine|CS-W006906

Structure of 1383481-11-5

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Description

7-Chloroimidazo[1,2-b]pyridazine is a heterocyclic compound featuring a chlorinated imidazopyridazine core. This electron-deficient scaffold integrates readily into medicinal chemistry campaigns, serving as a key building block for kinase inhibitors and CNS-targeted therapeutics. The chlorine substituent enhances metabolic stability and facilitates downstream functionalization via palladium-catalyzed cross-coupling reactions.

Application

7-Chloroimidazo[1,2-b]pyridazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to imidazopyridazine scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. The chlorine substituent facilitates nucleophilic substitution reactions, supporting late-stage functionalization. Its stability under standard synthetic conditions and compatibility with common coupling protocols make it a practical choice for modular library synthesis.

General Information

CAS No. 1383481-11-5
Cat. No. CS-W006906
Purity ≥98%
MDL No. MFCD24387377
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄ClN₃
Molecular Weight 153.57
Synonym(s) None
SMILES ClC1=CC2=NC=CN2N=C1

Computational Chemistry Data

TPSA 30.19
LogP 1.3827
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridazine compounds

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7-Chloroimidazo[1,2-b]pyridazine

CAS No. 1383481-11-5

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