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Structure of 138731-14-3
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This indole derivative features a carboxylic acid group at the 5-position and an ethoxycarbonyl substituent at the 2-position, enabling direct incorporation into peptide coupling or heterocyclic synthesis. The electron-deficient indole core enhances reactivity in electrophilic substitution, while the ester moiety offers stability under standard conditions.
2-(Ethoxycarbonyl)-1H-indole-5-carboxylic acid serves as a versatile building block for indole-based heterocycles, enabling direct functionalization at the C5 position. Its dual carboxylic acid and ester functionalities facilitate sequential transformations, including decarboxylation, amidation, and coupling reactions. The compound exhibits good bench stability and is compatible with standard synthetic protocols, making it well-suited for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: