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Structure of 138907-81-0
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1-(4-Fluorophenyl)-1H-pyrazole-4-carboxylic acid features a fluorinated aryl group conjugated to a pyrazole core, delivering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into bioactive molecules, enabling efficient coupling in peptide and small-molecule synthesis under standard conditions.
1-(4-Fluorophenyl)-1H-pyrazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its fluorinated aryl moiety enhances metabolic stability and membrane permeability, while the carboxylic acid group facilitates direct derivatization or amide formation under common peptide coupling conditions. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it suitable for scalable synthesis and structure–activity relationship studies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: