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Structure of 139022-25-6
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Imidazo[1,2-a]pyridine-6-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 6-position, enabling direct conjugation or derivatization. This scaffold combines enhanced planarity and electron-deficient character with improved solubility compared to related systems, making it valuable for medicinal chemistry and materials development.
Imidazo[1,2-a]pyridine-6-carboxylic acid serves as a versatile heterocyclic building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through standard amide coupling and derivatization protocols. The carboxylic acid functionality facilitates direct conjugation with amines, supports salt formation for improved solubility, and enables further functionalization via esterification or activation. Its rigid, planar structure enhances binding affinity in target-directed drug discovery, while the bench-stable nature simplifies handling and purification in routine synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: