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Structure of 1393330-40-9
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Propargyl-PEG5-NHS ester enables efficient conjugation of biomolecules via bioorthogonal click chemistry. The terminal alkyne group facilitates copper-catalyzed azide-alkyne cycloaddition, while the PEG5 spacer provides solubility and reduced non-specific binding. This reagent is stable under physiological conditions and ideal for labeling proteins, antibodies, and nucleic acids.
Propargyl-PEG5-NHS ester serves as a versatile bifunctional linker for conjugating biomolecules, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) via its terminal alkyne group. The PEG5 spacer provides enhanced solubility and reduced non-specific binding, while the NHS ester readily reacts with primary amines under physiological conditions. This reagent facilitates site-specific labeling and bioconjugation in peptide, protein, and oligonucleotide modifications, offering robust stability and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: