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Structure of 139399-64-7
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6-Bromoquinolin-8-ol features a bromine substituent at the 6-position and a hydroxyl group at the 8-position of the quinoline scaffold, enabling direct functionalization in cross-coupling reactions. This electron-deficient heteroaromatic system exhibits enhanced reactivity in palladium-catalyzed transformations while maintaining bench-stability under standard conditions.
6-Bromoquinolin-8-ol serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization via palladium-catalyzed cross-coupling reactions. Its bromine at the 6-position and phenolic hydroxyl at the 8-position provide orthogonal reactivity for sequential transformations, while the rigid quinoline scaffold enhances metabolic stability. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of kinase inhibitors, fluorescent probes, and advanced heterocyclic architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: