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CS-W001157 4
Total: USD 88.00

(Fmoc-Cys-OtBu)2 (disulfide bridge)

  • CAS No. 139592-37-3

  • Cat. No. CS-0154596
  • Purity≥96%
  • MDL No.MFCD28016692

*For research and further manufacturing use only, not for direct human use.

(Fmoc-Cys-OtBu)2 (disulfide bridge)|CS-0154596

Structure of 139592-37-3

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General Information

  • CAS No. 139592-37-3
  • Cat. No. CS-0154596
  • Purity ≥96%
  • MDL No. MFCD28016692
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₄H₄₈N₂O₈S₂
  • Molecular Weight 796.99
  • Synonym(s) None
  • SMILES O=C(OCC1C2=CC=CC=C2C3=CC=CC=C31)N[C@H](C(OC(C)(C)C)=O)CSSC[C@@H](C(OC(C)(C)C)=O)NC(OCC4C5=CC=CC=C5C6=CC=CC=C64)=O

Description

Fmoc-Cys-OtBu dimer features a disulfide bridge enabling controlled redox handling in peptide synthesis. This stable, bench-stable derivative integrates seamlessly into chain elongation protocols, offering reliable cysteine incorporation with minimal side reactivity.

Synthesis

  • Route1
    • Di-tert-butyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate)|CS-1389134
      62574-13-4
    • In-stock
      Fmoc-Osu Amino acid impurity|CS-1733136
      82911-69-1
    • ~75%
    • In-stock
      (Fmoc-Cys-OtBu)2 (disulfide bridge)|CS-0154596
      139592-37-3

    References

    • Tetrahedron, , vol. 58, # 44 p. 9101 - 9109
  • Route2
    • null|null
      28920-43-6
    • Di-tert-butyl 3,3'-disulfanediyl(2R,2'R)-bis(2-aminopropanoate)|CS-1389134
      62574-13-4
    • ~81%
    • In-stock
      (Fmoc-Cys-OtBu)2 (disulfide bridge)|CS-0154596
      139592-37-3

    References

    • Journal of Organic Chemistry, , vol. 68, # 21 p. 8185 - 8192
  • Route3
    • null|null
      540-88-5
    • ~%
    • In-stock
      (Fmoc-Cys-OtBu)2 (disulfide bridge)|CS-0154596
      139592-37-3

    References

    • Journal of Organic Chemistry, , vol. 68, # 21 p. 8185 - 8192

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   129.26
  • LogP   8.8658
  • H_Acceptors   10
  • H_Donors   2
  • Rotatable_Bonds   13

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