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Structure of 1398923-95-9
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4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol features a boronate ester group that enables efficient Suzuki-Miyaura coupling under mild conditions. The para-fluorine substituent enhances electrophilicity and improves metabolic stability in downstream applications. This bench-stable reagent integrates seamlessly into complex molecule synthesis workflows.
4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenol serves as a versatile boronate building block in Suzuki-Miyaura cross-coupling reactions. Its ortho-fluorinated aryl structure enables selective functionalization, while the pinacol boronate group offers excellent bench stability, ease of handling, and compatibility with diverse reaction conditions. The compound facilitates efficient C–C bond formation under mild catalytic systems, making it a reliable reagent for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: