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Structure of 1401222-64-7
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This morpholine derivative features a boronate ester group integrated with a sulfonamide linker, enabling efficient Suzuki-Miyaura coupling under standard conditions. The tetramethyl-1,3,2-dioxaborolane moiety imparts excellent stability and reactivity, while the electron-rich morpholine ring enhances solubility in polar solvents. This combination facilitates reliable incorporation into complex molecular architectures during synthetic workflows.
4-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)sulfonyl)morpholine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The morpholine sulfone moiety imparts excellent bench stability and solubility, while the pinacol boronate group enables efficient coupling with aryl halides under mild conditions. Its functional group tolerance and ease of purification make it a practical reagent for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: