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Structure of 1401464-07-0
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This azabicyclic scaffold integrates a protected amine and carboxylic acid within a rigid, electron-deficient framework. Designed for efficient peptide macrocyclization, it enables stable ring formation under standard conditions. The tert-butoxycarbonyl group offers orthogonal protection, while the endo configuration enhances conformational control in synthetic applications.
endo-3-[(tert-Butoxy)carbonyl]-3-azabicyclo[3.1.0]hexane-6-carboxylic acid serves as a versatile, bench-stable building block for the synthesis of constrained nitrogen-containing heterocycles. The protected amine and carboxylic acid functionalities enable orthogonal transformations, facilitating efficient access to medicinal chemistry scaffolds via standard coupling, hydrogenation, and cyclization protocols. Its rigid bicyclic framework supports stereocontrolled derivatization, making it well-suited for targeted compound library development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: