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CS-W001157 4
Total: USD 88.00

2-(Hydroxymethyl)-4-iodophenol

  • CAS No. 14056-07-6

  • Cat. No. CS-0163215
  • Purity≥98%
  • MDL No.None
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(Hydroxymethyl)-4-iodophenol|CS-0163215

Structure of 14056-07-6

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Description

2-(Hydroxymethyl)-4-iodophenol features a phenolic hydroxyl group paired with a para-iodinated aromatic ring and a reactive hydroxymethyl substituent. This combination enables direct functionalization in cross-coupling reactions or derivatization via the alcohol moiety. The molecule exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols.

Application

2-(Hydroxymethyl)-4-iodophenol serves as a versatile building block for Suzuki-Miyaura and Sonogashira coupling reactions, enabling efficient construction of biaryl and alkynylated scaffolds. The phenolic hydroxyl group offers orthogonal reactivity for derivatization, while the iodide facilitates reliable cross-coupling under mild conditions. Bench-stable and amenable to standard purification protocols, it functions effectively in the synthesis of functionalized heterocycles and advanced intermediates for medicinal chemistry applications.

General Information

  • CAS No. 14056-07-6
  • Cat. No. CS-0163215
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇IO₂
  • Molecular Weight 250.03
  • Synonym(s) BENZENEMETHANOL, 2-HYDROXY-5-IODO
  • SMILES OC1=CC=C(I)C=C1CO

Computational Chemistry Data

  • TPSA   40.46
  • LogP   1.4891
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

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