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Structure of 14056-07-6
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2-(Hydroxymethyl)-4-iodophenol features a phenolic hydroxyl group paired with a para-iodinated aromatic ring and a reactive hydroxymethyl substituent. This combination enables direct functionalization in cross-coupling reactions or derivatization via the alcohol moiety. The molecule exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols.
2-(Hydroxymethyl)-4-iodophenol serves as a versatile building block for Suzuki-Miyaura and Sonogashira coupling reactions, enabling efficient construction of biaryl and alkynylated scaffolds. The phenolic hydroxyl group offers orthogonal reactivity for derivatization, while the iodide facilitates reliable cross-coupling under mild conditions. Bench-stable and amenable to standard purification protocols, it functions effectively in the synthesis of functionalized heterocycles and advanced intermediates for medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H332
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
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Lot numbers can be found on the outside label of a product: