Lot numbers can be found on the outside label of a product:
Ethyl 4-chlorophenylacetate
-
CAS No. 14062-24-9
- Cat. No. CS-W022691
- Purity≥97%
- MDL No.MFCD00018791
*For research and further manufacturing use only, not for direct human use.
Structure of 14062-24-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 14062-24-9
- Cat. No. CS-W022691
- Purity ≥97%
- MDL No. MFCD00018791
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₀H₁₁ClO₂
- Molecular Weight 198.65
- Synonym(s) Ethyl p-chlorophenylacetate
- SMILES C1=CC(=CC=C1CC(OCC)=O)Cl
Description
Ethyl 4-chlorophenylacetate is a bench-stable ester featuring a para-chlorinated phenyl moiety that enables direct integration into Suzuki-Miyaura coupling workflows. This electron-deficient aryl acceptor couples efficiently with boronic acids under palladium catalysis, delivering functionalized biaryl scaffolds with minimal purification burden.
Application
Ethyl 4-chlorophenylacetate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of pharmaceutically relevant arylacetic acid derivatives. Its stability under standard reaction conditions and compatibility with diverse coupling and functionalization processes facilitate straightforward access to substituted phenylacetic scaffolds. The ethyl ester group provides a handle for selective transformations, while the para-chloro substituent offers a site for nucleophilic substitution or cross-coupling reactions, making it a practical intermediate in medicinal chemistry and process development workflows.
Synthesis
-
Route1
-
In-stock
1878-66-6 -
64-17-5 - ~97%
-
In-stock
14062-24-9
References
-
ARRAY BIOPHARMA INC. Patent: WO2005/51304 A2, 2005 ; Location in patent: Page/Page column 105 ; WO 2005/051304 A2
-
-
Route2
-
In-stock
1878-66-6
- ~88%
-
In-stock
14062-24-9
References
-
Hoffman-La Roche Inc. Patent: US6610846 B1, 2003 ; US 6610846 B1
-
-
Route3
-
64-17-5
-
201230-82-2
-
106-43-4
- ~90%
-
In-stock
14062-24-9
References
-
Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences; Huang, Hanmin; Xia, Chungu; Xie, Pan Patent: US2013/303798 A1, 2013 ; Location in patent: Paragraph 0062; 0063 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 26.3
- LogP 2.4456
- H_Acceptors 2
- H_Donors 0
- Rotatable_Bonds 3
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- Ethyl 4-chlorophenylacetate sigmaEthyl 4-chlorophenylacetate manufacturerEthyl 4-chlorophenylacetate priceEthyl 4-chlorophenylacetate structureEthyl 4-chlorophenylacetate SDSbuy Ethyl 4-chlorophenylacetateEthyl 4-chlorophenylacetate supplierEthyl 4-chlorophenylacetate usesEthyl 4-chlorophenylacetate molecular weightprice of Ethyl 4-chlorophenylacetateEthyl 4-chlorophenylacetate chemical name formula of Ethyl 4-chlorophenylacetate