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Structure of 1408282-26-7
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8-Fluoro-1,3,4,5-tetrahydro-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one features a fluorinated pyrrolobenzazepinone core with enhanced electron-withdrawing character from the fluoro substituent. This scaffold integrates readily into medicinal chemistry libraries, offering improved metabolic stability and targeted binding affinity in CNS-directed compound development.
8-Fluoro-1,3,4,5-tetrahydro-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one serves as a structurally defined heterocyclic building block for medicinal chemistry campaigns targeting CNS-active compounds. The scaffold features a fluorinated indole-like core with a ketone functionality at C6, enabling downstream derivatization via nucleophilic addition or reductive amination. Bench-stable and compatible with standard synthetic workflows, it facilitates the construction of complex polycyclic architectures relevant to kinase inhibitor and receptor modulator development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: