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CS-W001157 4
Total: USD 88.00

2-Thiouracil

  • CAS No. 141-90-2

  • Cat. No. CS-2704
  • Molecule weightNone
  • Purity≥98%
  • MDL No.MFCD00006039

*For research and further manufacturing use only, not for direct human use.

2-Thiouracil|CS-2704

Structure of 141-90-2

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General Information

  • CAS No. 141-90-2
  • Cat. No. CS-2704
  • Purity ≥98%
  • MDL No. MFCD00006039
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄N₂OS
  • Molecular Weight None
  • Synonym(s) Thiouracil
  • SMILES O=C(C=CN1)NC1=S

Description

Thiolated uracil derivative, 2-Thiouracil (CAS 141-90-2), inhibits thyroid hormone synthesis by disrupting iodination of thyroglobulin precursors in the follicular lumen.

Application

2-Thiouracil (CAS 141-90-2) drives the synthesis of silver colloids and film substrates for surface-enhanced Raman scattering studies by enabling precise nanoparticle stabilization. It also facilitates electro-oxidation analysis at TiO₂-modified gold electrodes. Researchers leverage this compound to probe methylation effects on triplet-state dynamics and deactivation pathways through time-resolved photoelectron spectroscopy.

Synthesis

  • Route1
    • null|null
      1257309-84-4
    • ~70%
    • In-stock
      2-Thiouracil|CS-2704
      141-90-2
    • N-(1,3-Dihydroxypropan-2-yl)acetamide|CS-0247899
      2655-79-0

    References

    • Nucleosides, Nucleotides and Nucleic Acids, , vol. 29, # 10 p. 768 - 785
  • Route2

    References

    • Bretner; Kulikowski; Dzik; Balinska; Rode; Shugar Journal of Medicinal Chemistry, 1993 , vol. 36, # 23 p. 3611 - 3617
  • Route3
    • In-stock
      Ethyl 3,3-diethoxypropionate|CS-W015890
      10601-80-6
    • null|null
      17356-08-0
    • ~%
    • In-stock
      2-Thiouracil|CS-2704
      141-90-2

    References

    • Journal of the American Chemical Society, , vol. 72, p. 2587,2593

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H351
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   48.65
  • LogP   0.43249
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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