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Structure of 14143-26-1
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4-Hydroxy-2-methylbenzonitrile features a strategically positioned hydroxyl group and nitrile moiety on a methyl-substituted benzene ring, enabling selective functionalization in synthetic routes. This electron-deficient aromatic scaffold delivers enhanced reactivity in coupling processes and serves as a robust building block for bioactive molecule synthesis under standard conditions.
4-Hydroxy-2-methylbenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the phenolic hydroxyl group. Its ortho-methyl and cyano substituents provide steric and electronic modulation for downstream transformations. The compound exhibits good bench stability and facilitates efficient coupling reactions, purification via recrystallization, and compatibility with standard protecting group strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: