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CS-W001157 4
Total: USD 88.00

2-(Pyridin-2-yloxy)benzaldehyde

  • CAS No. 141580-71-4

  • Cat. No. CS-0074744
  • Purity≥98%
  • MDL No.None
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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(Pyridin-2-yloxy)benzaldehyde|CS-0074744

Structure of 141580-71-4

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Description

This pyridin-2-yloxy-substituted benzaldehyde features a strategically positioned aldehyde group flanked by electron-rich aromatic systems, enabling direct integration into Suzuki-Miyaura coupling and Ullmann-type cross-coupling reactions. The ortho-arranged heterocyclic oxygen enhances chelation potential in transition metal complexes, while maintaining bench-stable handling under standard conditions.

Application

2-(Pyridin-2-yloxy)benzaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient construction of biaryl and heterocyclic scaffolds. Its ortho-heterocyclic motif provides enhanced rigidity and polarity, while the aldehyde functionality facilitates imine formation, reductive amination, and coupling reactions. Bench-stable and readily purified by column chromatography, it exhibits broad functional group tolerance in standard synthetic workflows.

General Information

  • CAS No. 141580-71-4
  • Cat. No. CS-0074744
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉NO₂
  • Molecular Weight 199.21
  • Synonym(s) 2-(PYRID-2-YLOXY)BENZALDEHYDE
  • SMILES O=CC1=CC=CC=C1OC2=CC=CC=N2

Computational Chemistry Data

  • TPSA   39.19
  • LogP   2.6864
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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