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Structure of 142166-00-5
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Methyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylate features a fused benzoxazine core with a ketone at C3 and a methyl ester at C7, delivering enhanced stability and reactivity in heterocyclic synthesis. This bench-stable scaffold integrates readily into complex molecular architectures via nucleophilic addition or transition-metal-catalyzed coupling, enabling efficient access to bioactive analogs and functionalized materials.
Methyl 3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylate serves as a versatile building block for the synthesis of substituted benzoxazines and related heterocyclic scaffolds. Its functionality enables facile derivatization at the C3 carbonyl and C7 ester positions, supporting diverse transformations including nucleophilic additions, reductive aminations, and coupling reactions. The compound exhibits good bench stability and ease of purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330
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Lot numbers can be found on the outside label of a product: