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Structure of 14229-27-7
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3-Amino-5,6-dichloropyrazine-2-carboxamide features a pyrazine core bearing electron-withdrawing chloro groups and a carboxamide functionality, enabling direct integration into heterocyclic scaffolds. The amino substituent supports further derivatization, while the dichloro pattern enhances reactivity in cross-coupling and nucleophilic substitution processes. This compound serves as a key intermediate in the synthesis of bioactive nitrogen-containing systems.
3-Amino-5,6-dichloropyrazine-2-carboxamide serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through nucleophilic substitution and coupling reactions. Its dichloro-pyrazine core offers high reactivity for late-stage functionalization, while the amino and carboxamide groups provide orthogonal handles for conjugation. Bench-stable and amenable to standard purification methods, it facilitates efficient synthesis of kinase inhibitors and other pharmaceutical scaffolds.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361-P405-P501
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Lot numbers can be found on the outside label of a product: