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Structure of 1423029-80-4
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6-Isopropylnicotinic acid hydrochloride features a sterically hindered isopropyl group at the pyridine ring's 6-position, enhancing metabolic stability. This bench-stable salt form improves solubility and handling in synthetic workflows, enabling efficient integration into pharmaceutical intermediates and bioactive molecule scaffolds.
6-Isopropylnicotinic acid hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted nicotinamide derivatives and heterocyclic scaffolds. Its well-defined functional group tolerance facilitates direct amidation and coupling reactions, while the protonated form enhances solubility and stability during purification. The isopropyl substituent provides steric bulk and metabolic stability, making it valuable for optimizing pharmacokinetic profiles in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: