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Structure of 1423031-89-3
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Sodium 1-(prop-2-enoyl)piperidine-4-carboxylate features a conjugated enamide system linked to a piperidine scaffold, enabling efficient Michael addition reactions. The carboxylate counterion enhances solubility in polar solvents, facilitating use in aqueous or mixed solvent systems. This stable, bench-ready reagent integrates readily into synthetic sequences requiring nucleophilic attack at α,β-unsaturated carbonyls.
Sodium 1-(prop-2-enoyl)piperidine-4-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of bioactive heterocycles and peptide-like scaffolds. Its conjugated enamide functionality facilitates Michael additions, cycloadditions, and palladium-catalyzed couplings under mild conditions. The carboxylate counterion enhances solubility and stability, simplifying purification and handling in aqueous or mixed solvent systems. This reagent is particularly valuable for late-stage functionalization and scaffold diversification in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: