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Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II)

  • CAS No. 14267-08-4

  • Cat. No. CS-0080778
  • Molecule weight293.53
  • Purity≥98%
  • MDL No.MFCD00075317

*For research and further manufacturing use only, not for direct human use.

Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II)|CS-0080778

Structure of 14267-08-4

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General Information

  • CAS No. 14267-08-4
  • Cat. No. CS-0080778
  • Purity ≥98%
  • MDL No. MFCD00075317
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₆Cl₂N₂Pd
  • Molecular Weight 293.53
  • Synonym(s) Dichloro(N,N,N,N-tetramethylethylenediamine)palladium(II)
  • SMILES C[N](C)([Pd](Cl)1Cl)CC[N]1(C)C

Description

Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II) delivers a stable, moisture-tolerant palladium source for cross-coupling reactions. The tetramethylethylenediamine ligand enhances solubility and reactivity in polar solvents, enabling efficient C–C bond formation under mild conditions. This complex integrates seamlessly into Suzuki-Miyaura and Stille coupling workflows, offering reliable performance with minimal decomposition.

Application

Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II) serves as a stable, bench-ready precatalyst for cross-coupling reactions. It facilitates efficient Suzuki, Stille, and Negishi couplings with broad functional group tolerance. The tetramethylethylenediamine ligand enhances solubility and reactivity while enabling straightforward handling and purification. This catalyst is well-suited for both academic and industrial-scale synthesis workflows.

Synthesis

  • Route1
    • null|null
      21264-30-2
    • null|null
      110-18-9
    • ~98%
    • In-stock
      Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II)|CS-0080778
      14267-08-4

    References

    • Biscoe, Mark R.; Fors, Brett P.; Buchwald, Stephen L. Journal of the American Chemical Society, 2008 , vol. 130, # 21 p. 6686 - 6687
  • Route2
    • Bis(acetonitrile)palladium(II) dichloride, High quality|CS-1383731
      14592-56-4
    • null|null
      110-18-9
    • ~97%
    • In-stock
      Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II)|CS-0080778
      14267-08-4

    References

    • Zhao, Qing; Li, Chengxi; Senanayake, Chris H.; Tang, Wenjun Chemistry - A European Journal, 2013 , vol. 19, # 7 p. 2261 - 2265
  • Route3
    • null|null
      110-18-9
    • null|null
      7647-10-1
    • ~90%
    • In-stock
      Dichloro(N,N,N',N'-tetramethylethylenediamine)palladium(II)|CS-0080778
      14267-08-4

    References

    • Graaf, Wim de; Boersma, Jaap; Smeets, Wilberth J. J.; Spek, Anthony L.; Koten, Gerard van Organometallics, 1989 , vol. 8, p. 2907 - 2917

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   N/A

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