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Structure of 1427377-75-0
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7-Bromo-6-fluoro-1H-indazole is a fluorinated indazole derivative featuring complementary halogen substituents at the 6- and 7-positions. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering enhanced reactivity and selectivity in C–H functionalization. The strategic placement of bromine and fluorine enables orthogonal derivatization pathways, facilitating rapid access to complex molecular architectures in medicinal chemistry and materials science.
7-Bromo-6-fluoro-1H-indazole serves as a valuable heterocyclic building block in medicinal chemistry, enabling direct functionalization at multiple sites due to its complementary halogen reactivity. The bromo and fluoro substituents facilitate palladium-catalyzed cross-coupling reactions and nucleophilic aromatic substitution, while maintaining bench stability and compatibility with standard purification protocols. Its defined electronic profile supports efficient incorporation into diverse API scaffolds and targeted compound libraries.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: