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Structure of 1427433-22-4
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3-Bromo-2-fluoro-6-methyl-benzoic acid features a sterically hindered aromatic core with complementary halogen and methyl substituents, enabling selective coupling reactions. The carboxylic acid group provides a robust handle for derivatization under standard conditions, while the electron-withdrawing bromo and fluoro functionalities enhance reactivity in transition-metal-catalyzed transformations.
3-Bromo-2-fluoro-6-methyl-benzoic acid serves as a versatile building block for the synthesis of substituted aromatic systems, particularly in medicinal chemistry and agrochemical research. Its orthogonal halogenation pattern (Br at C3, F at C2, Me at C6) enables selective cross-coupling reactions, including Suzuki and Stille couplings, while the carboxylic acid group facilitates direct derivatization or incorporation into biologically active scaffolds. The compound exhibits good bench stability and is compatible with standard purification techniques.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: