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Structure of 143259-56-7
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tert-Butyl 3-bromo-1H-indole-1-carboxylate features a brominated indole core with a robust tert-butyl ester handle, enabling direct incorporation into cross-coupling reactions. The electron-deficient bromine at the 3-position facilitates palladium-catalyzed functionalization, while the bench-stable ester group resists hydrolysis under standard conditions.
tert-Butyl 3-bromo-1H-indole-1-carboxylate serves as a versatile building block for indole-based scaffolds, enabling direct functionalization at the C3 position via palladium-catalyzed cross-coupling reactions. The tert-butyl carbamate group provides excellent stability and ease of removal under mild acidic conditions, while the bromine substituent offers high reactivity in standard coupling protocols. This compound facilitates efficient access to substituted indoles used in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: