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Structure of 143328-24-9
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This cyclopentane carboxylic acid derivative features a para-brominated phenyl group, offering enhanced electron-withdrawing character and improved solubility in organic media. The rigid cyclopentane scaffold provides conformational stability, while the carboxylic acid functionality enables direct coupling reactions. Ideal for medicinal chemistry scaffolds and pharmaceutical intermediates requiring halogenated aromatic handles.
1-(4-Bromophenyl)cyclopentane-1-carboxylic acid serves as a versatile building block for medicinal chemistry and materials synthesis, enabling efficient construction of biaryl-containing scaffolds via palladium-catalyzed cross-coupling. The carboxylic acid functionality offers direct handle for derivatization, while the bromophenyl group provides orthogonal reactivity in Suzuki, Stille, or Negishi coupling reactions. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows requiring functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: