2-Chloro-1-methylpyridinium iodide

Name: 2-Chloro-1-methylpyridinium iodide
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CAS No. 14338-32-0
Cat. No. CS-D1115
Purity≥96%
MDL No.MFCD00011984

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2-Chloro-1-methylpyridinium iodide|CS-D1115

Structure of 14338-32-0

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Description

2-Chloro-1-methylpyridinium iodide (Mukaiyama reagent), is a commonly used reagent in organic synthesis for the activation of the hydroxy group of alcohols and carboxylic acids. It is used to synthesize derivatives of esters, lactones, amides, lactams, and ketenes from the corresponding carboxylic acids. It is also used as an efficient coupling reagent in the synthesis of peptides because of its low toxicity, simple reaction conditions, and also less expensive than EDC.2-Chloro-1-methylpyridinium iodide (CMPI) can be used as: A dehydrating agent for the conversion of various aldoximes to nitriles, and alcohols into alkyl thiocyanates. A cross-linking agent to fabricate biodegradable cross-linked hyaluronic acid film and gelatin membranes for biomedical applications. A condensing agent to synthesize various -lactams from -amino acids.

General Information

CAS No. 14338-32-0
Cat. No. CS-D1115
Purity ≥96%
MDL No. MFCD00011984
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₇ClIN
Molecular Weight 255.48
Synonym(s) 1-Methyl-2-chloropyridinium iodide; 2-Chloro-1-methylpyridinium iodide; N-Methyl-2-chloropyridinium iodide Mukaiyamas
SMILES ClC1=[N+](C)C=CC=C1.[I-]

Computational Chemistry Data

TPSA 3.88
LogP -1.8315
H_Acceptors 0
H_Donors 0
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

General Reagents Ionic Liquids Pyridine Ionic Liquid

General Reagents Alkylating Reagents

Chemical Biology Glycoscience Reagents for Oligosaccharide Synthesis

Chemical Synthesis Specialty Synthesis Ionic Liquids Pyridinium Salts

Chemical Synthesis Synthetic Reagents C-X(Non-Halogen) Bond Formation Alkylation (Esterification)

Chemical Synthesis Synthetic Reagents Coupling Active Esters, Additives

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2-Chloro-1-methylpyridinium iodide

CAS No. 14338-32-0

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