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CS-W001157 4
Total: USD 88.00

(5-Methylbenzofuran-2-yl)boronic acid

  • CAS No. 143381-72-0

  • Cat. No. CS-0043723
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(5-Methylbenzofuran-2-yl)boronic acid|CS-0043723

Structure of 143381-72-0

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General Information

  • CAS No. 143381-72-0
  • Cat. No. CS-0043723
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉BO₃
  • Molecular Weight 175.98
  • Synonym(s) Boronic acid, (5-methyl-2-benzofuranyl)- (9CI)
  • SMILES CC1=CC=C(OC(B(O)O)=C2)C2=C1

Description

This boronate moiety integrates readily into Suzuki-Miyaura cross-coupling reactions under standard conditions, delivering functionalized aryl products with high efficiency. The methyl substituent enhances electron density at the coupling site while maintaining bench-stable handling properties.

Application

(5-Methylbenzofuran-2-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation with aryl and vinyl halides. Its benzofuran scaffold provides structural relevance to bioactive molecules and pharmaceutical intermediates. The boronic acid moiety offers excellent bench stability, compatibility with diverse functional groups, and straightforward purification via crystallization or flash chromatography, making it ideal for iterative synthesis in medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.6
  • LogP   0.42102
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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