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Structure of 14339-33-4
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3-Chloro-1H-pyrazole is a bench-stable heterocyclic building block featuring a chlorine substituent at the 3-position, enabling direct functionalization in cross-coupling and electrophilic substitution reactions. This electron-deficient pyrazole integrates readily into pharmaceutical intermediates and agrochemical scaffolds due to its reactivity profile and compatibility with diverse synthetic transformations under standard conditions.
3-Chloro-1H-pyrazole serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling efficient access to functionalized pyrazole scaffolds. Its chlorine substituent facilitates electrophilic substitution and transition-metal-catalyzed coupling reactions, while the pyrazole core offers favorable metabolic stability and hydrogen-bonding capacity. The compound exhibits good bench stability and is compatible with common purification methods, making it ideal for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: