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Structure of 1433975-21-3
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Fmoc-D-Aph(tBuCbm)-OH is a sterically hindered, bench-stable amino acid derivative featuring a trifluoromethylated benzyl side chain. This protected D-configured residue integrates efficiently into peptide chains under standard coupling conditions, offering enhanced resistance to metabolic degradation in bioactive sequences.
Fmoc-D-Aph(tBuCbm)-OH serves as a key building block for the synthesis of complex peptide architectures, particularly in the development of macrocyclic and constrained peptides. The D-configured aphthoic acid derivative with orthogonal tBuCbm protection enables selective coupling and late-stage deprotection, facilitating efficient solid-phase peptide synthesis. Its bench-stable Fmoc group and robust tBuCbm deprotection profile support high-purity product formation with minimal side reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: