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Structure of 1435-54-7
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1,3-Dibromo-2-fluorobenzene is a fluorinated aromatic building block featuring two bromine substituents at meta positions and a fluorine atom at the ortho position. This configuration imparts enhanced electronic modulation and directional control in cross-coupling reactions. The molecule exhibits excellent stability under standard conditions and integrates readily into complex heterocyclic frameworks via palladium-catalyzed transformations.
1,3-Dibromo-2-fluorobenzene serves as a valuable building block for the synthesis of fluorinated heterocycles and functionalized aromatic systems. Its orthogonal reactivity profile enables selective cross-coupling transformations, particularly in palladium-catalyzed processes, while maintaining bench stability and ease of purification. The molecule functions effectively in Suzuki-Miyaura and Negishi couplings, facilitating access to complex pharmaceutical intermediates and agrochemical scaffolds with high regiocontrol.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: