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CS-W001157 4
Total: USD 88.00

Hydroquinidine

  • CAS No. 1435-55-8

  • Cat. No. CS-4491
  • Molecule weight326.44
  • Purity≥97%
  • MDL No.MFCD00135599

*For research and further manufacturing use only, not for direct human use.

Hydroquinidine|CS-4491

Structure of 1435-55-8

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General Information

  • CAS No. 1435-55-8
  • Cat. No. CS-4491
  • Purity ≥97%
  • MDL No. MFCD00135599
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₆N₂O₂
  • Molecular Weight 326.44
  • Synonym(s) Dihydroquinidine; (+)-Hydroquinidine; Hydroconquinine
  • SMILES O[C@@H](C1=CC=NC2=C1C=C(OC)C=C2)[C@]3([H])[N@](C[C@@H]4CC)CC[C@H]4C3

Description

Hydroquinidine, a cinchona alkaloid, is a structural analog of quinidine. It shows antiarrhythmic effect.Hydroquinidine can be used as a chiral catalyst to prepare:Enantioselective axially chiral phosphamides by N-allylic alkylation reaction between Morita-Baylis-Hillamn (MBH) carbonate and phosphamides.Enantioselective -amino phosphonates by hydrophosphonylation of N-aryl ketimines.Enantioselective -hydrazino esters by -hydrazination of 3-oxoindolines using azodicarboxylate via aza-Michael reaction.

Synthesis

  • Route1

    References

    • Chemische Berichte, , vol. 45, p. 3317

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

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Computational Chemistry Data

  • TPSA   45.59
  • LogP   3.3972
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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