(2S,2'S,3S,3'S)-WingPhos

Name: (2S,2'S,3S,3'S)-WingPhos
Brand: ChemScene
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CAS No. 1435940-19-4
Cat. No. CS-0020506
Purity≥97%
MDL No.MFCD31630708

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 1435940-19-4

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Description

(2S,2'S,3S,3'S)-WingPhos is a sterically tuned, bench-stable phosphine ligand featuring a rigid biaryl backbone with strategically positioned substituents. This configuration enhances stability and electron density while promoting efficient palladium-catalyzed cross-coupling reactions under mild conditions. The ligand excels in challenging C–O and C–N bond formations, offering high selectivity and catalyst longevity in complex molecule synthesis.

Application

(2S,2'S,3S,3'S)-WingPhos serves as a highly effective, bench-stable phosphine ligand in palladium-catalyzed cross-coupling reactions. Its rigid, sterically defined structure enables selective C–C and C–heteroatom bond formation under mild conditions, with excellent functional group tolerance and consistent performance in Suzuki-Miyaura, Negishi, and Stille couplings. Designed for reproducible results in complex molecule synthesis, it facilitates efficient catalyst activation and minimizes decomposition pathways during scale-up.

General Information

CAS No. 1435940-19-4
Cat. No. CS-0020506
Purity ≥97%
MDL No. MFCD31630708
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅₀H₄₄O₂P₂
Molecular Weight 738.83
Synonym(s) (2S,2S’,3S,3S’)-WingPhos
SMILES [H][C@]1([C@]2([H])[P@@](C(C)(C)C)C(C(C3=C(C=CC=C4)C4=CC5=C3C=CC=C5)=CC=C6)=C6O2)[P@](C(C)(C)C)C7=C(C8=C(C=CC=C9)C9=CC%10=C8C=CC=C%10)C=CC=C7O1

Computational Chemistry Data

TPSA 18.46
LogP 13.582
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Key Words

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(2S,2'S,3S,3'S)-WingPhos

CAS No. 1435940-19-4

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