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Structure of 14381-51-2
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3-Bromobenzene-1,2-diol features a bromine substituent at the meta position relative to a vicinal diol system, delivering enhanced reactivity in electrophilic substitution and enabling selective functionalization. The ortho-diol moiety facilitates chelation and stabilization in transition metal-catalyzed transformations. This compound serves as a valuable intermediate in the synthesis of bioactive heterocycles and complex aromatic scaffolds.
3-Bromobenzene-1,2-diol serves as a versatile ortho-dihydroxy building block for the synthesis of bioactive heterocycles and functionalized aromatics. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, while the adjacent hydroxyl groups facilitate directed metalation, electrophilic substitution, or protection strategies. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, making it well-suited for iterative synthetic sequences in medicinal chemistry and materials development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: