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Structure of 143879-80-5
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2,3,4-Trifluorobenzonitrile features a trifluorinated aromatic ring paired with a nitrile group, delivering enhanced electron-withdrawal and metabolic stability. This combination enables efficient incorporation into pharmaceutical scaffolds and advanced synthetic intermediates under standard conditions.
2,3,4-Trifluorobenzonitrile serves as a versatile building block in medicinal chemistry and materials science, enabling direct functionalization at the aromatic ring due to its electron-deficient nature. The nitrile group facilitates nucleophilic substitution and transition-metal-catalyzed coupling reactions, while the trifluoromethyl substituents enhance metabolic stability and modulate electronic properties. Its bench-stable solid form simplifies handling and purification in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: