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CS-W001157 4
Total: USD 88.00

Terephthalimidamide dihydrochloride

  • CAS No. 14401-56-0

  • Cat. No. CS-0111307
  • Purity≥95%
  • MDL No.MFCD00136761

*For research and further manufacturing use only, not for direct human use.

Terephthalimidamide dihydrochloride|CS-0111307

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General Information

  • CAS No. 14401-56-0
  • Cat. No. CS-0111307
  • Purity ≥95%
  • MDL No. MFCD00136761
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂Cl₂N₄
  • Molecular Weight 235.11
  • Synonym(s) Terephthalimidamidedihydrochloride
  • SMILES N=C(C1=CC=C(C(N)=N)C=C1)N.[H]Cl.[H]Cl

Description

Terephthalimidamide dihydrochloride features a rigid aromatic core with two amide functionalities, enabling robust hydrogen bonding and enhanced solubility in aqueous and polar organic media. This bench-stable salt form facilitates straightforward handling and integration into synthetic workflows involving peptide mimetics, kinase inhibitors, or supramolecular architectures.

Application

Terephthalimidamide dihydrochloride serves as a stable, bench-ready building block for the synthesis of aromatic amides and heterocyclic scaffolds. Its dual amide functionalities enable efficient coupling reactions and facilitate incorporation into pharmaceutical intermediates. The dihydrochloride salt enhances solubility and handling, while maintaining compatibility with standard reaction conditions across diverse synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   99.74
  • LogP   1.09834
  • H_Acceptors   2
  • H_Donors   4
  • Rotatable_Bonds   2

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