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CS-W001157 4
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(R)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid

  • CAS No. 144085-23-4

  • Cat. No. CS-0006947
  • Purity≥95%
  • MDL No.MFCD01076221

*For research and further manufacturing use only, not for direct human use.

(R)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid|CS-0006947

Structure of 144085-23-4

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General Information

  • CAS No. 144085-23-4
  • Cat. No. CS-0006947
  • Purity ≥95%
  • MDL No. MFCD01076221
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₁NO₄
  • Molecular Weight 255.31
  • Synonym(s) BOC-(R)--ALLYL-PRO-OH
  • SMILES OC([C@@]1(CC=C)N(C(OC(C)(C)C)=O)CCC1)=O

Synthesis

  • Route1

    References

    • Khalil, Ehab M.; Subasinghe, Nalin L.; Johnson, Rodney L. Tetrahedron Letters, 1996 , vol. 37, # 20 p. 3441 - 3444
  • Route2
    • 1-(tert-Butyl) 2-methyl (R)-2-allylpyrrolidine-1,2-dicarboxylate|CS-M1775
      112348-45-5
    • ~80%
    • (R)-2-Allyl-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid|CS-0006947
      144085-23-4

    References

    • Bittermann, Holger; Einsiedel, Juergen; Huebner, Harald; Gmeiner, Peter Journal of Medicinal Chemistry, 2004 , vol. 47, # 22 p. 5587 - 5590
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 47, # 22 p. 5587 - 5590

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   2.4168
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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