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Structure of 1443110-01-7
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This brominated cyclobutyl ether integrates a reactive alkylating handle, enabling direct functionalization in cross-coupling and nucleophilic substitution processes. The benzyl-linked cyclobutane ring imparts rigidity and enhanced metabolic stability, while the terminal bromide facilitates efficient C–C bond formation under standard conditions.
[(3-Bromocyclobutoxy)methyl]benzene serves as a versatile building block for the synthesis of functionalized cyclobutane derivatives, enabling efficient C–O bond formation in Suzuki-Miyaura and Stille coupling reactions. Its bromine substituent facilitates palladium-catalyzed cross-coupling with boronic acids and stannanes, while the benzyl-linked cyclobutoxy moiety offers enhanced stability and ease of purification. This compound functions as a key intermediate in constructing bioactive heterocyclic scaffolds and medicinal chemistry libraries.
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GHS No : GHS06,GHS08
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Signal Word : Danger
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UN#: 2810
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H311-H331-H341
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Precautionary Statements : P233-P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P405-P501
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Lot numbers can be found on the outside label of a product: