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Structure of 144528-23-4
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1-Methyl-1H-indazol-4-ol features a fused bicyclic core with a phenolic hydroxyl group at the 4-position and a methyl substituent at the 1-nitrogen, conferring enhanced solubility and metabolic stability. This scaffold serves as a privileged motif in medicinal chemistry, integrating readily into kinase inhibitors and bioactive heterocycles. The compound exhibits bench-stable handling characteristics under standard conditions.
1-Methyl-1H-indazol-4-ol serves as a versatile building block for medicinal chemistry campaigns, enabling direct incorporation into bioactive heterocycles via standard coupling and functionalization protocols. Its phenolic hydroxyl group facilitates efficient derivatization, while the methylated indazolone core exhibits enhanced bench stability and favorable solubility profiles. The compound functions effectively in Suzuki-Miyaura, Ullmann, and amide bond formation reactions, supporting rapid access to diverse scaffolds in drug discovery workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: