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Structure of 1448440-50-3
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(S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate features a sterically hindered pyrrolidine core with dual fluorine atoms enhancing metabolic stability. The cyano group enables direct incorporation into bioactive scaffolds, while the carbamate moiety offers convenient protection for amine-based intermediates in synthetic sequences. This chiral building block integrates readily into medicinal chemistry campaigns targeting CNS and oncology therapeutics under standard conditions.
(S)-tert-Butyl (2-(2-cyano-4,4-difluoropyrrolidin-1-yl)-2-oxoethyl)carbamate serves as a versatile building block for the synthesis of fluorinated pyrrolidine-containing scaffolds. Its cyano and carbamate functionalities enable selective transformations in medicinal chemistry workflows. The molecule exhibits bench stability and facilitates efficient incorporation into complex heterocycles, supporting applications in API development requiring enhanced metabolic resistance and targeted bioavailability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: