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Structure of 1449521-05-4
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This phosphonium salt features a highly electrophilic carbon center stabilized by two fluorine atoms and a triphenylphosphonium group. It serves as a key reagent in nucleophilic substitution reactions, enabling efficient C–C bond formation under mild conditions. The fluorinated α-carbon enhances reactivity while maintaining bench stability.
2,2-Difluoro-2-(triphenylphosphonio)acetate serves as a stable, bench-ready phosphonium salt enabling efficient Wittig-type olefination reactions. Its difluoromethylene group enhances electrophilicity and stabilizes the betaine intermediate, facilitating high-yielding synthesis of α,α-difluoroalkenes—key motifs in medicinal chemistry and agrochemical development. The triphenylphosphonium moiety ensures compatibility with standard carbonyl addition protocols, offering predictable reactivity and straightforward purification.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: