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CS-W001157 4
Total: USD 88.00

20α-Dihydroprogesterone

  • CAS No. 145-14-2

  • Cat. No. CS-0059471
  • Purity≥98%
  • MDL No.MFCD00009823

*For research and further manufacturing use only, not for direct human use.

20α-Dihydroprogesterone|CS-0059471

Structure of 145-14-2

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General Information

  • CAS No. 145-14-2
  • Cat. No. CS-0059471
  • Purity ≥98%
  • MDL No. MFCD00009823
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₃₂O₂
  • Molecular Weight 316.48
  • Synonym(s) 20-OH-P
  • SMILES C[C@@]12[C@]3([H])[C@](CCC1=CC(CC2)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@@H](O)C)C

Description

Plant cell division factor. Stimulates Ca2+ influx (Km = 1 nM) by moss protoplasts. Reported to induce positive inotropic effects through activation of P2-purinergic receptors. When complexed with copper, catalyzes molecular oxygen dismutation at physiological pH.

Synthesis

  • Route1
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      15780-23-1
    • ~%
    • 20α-Dihydroprogesterone|CS-0059471
      145-14-2

    References

    • WO2009/108804 A2, ; Page/Page column 107; 108 ;
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 52, # 19 p. 6012 - 6023
  • Route3
    • null|null
      74996-87-5
    • ~%
    • 20α-Dihydroprogesterone|CS-0059471
      145-14-2

    References

    • Journal of the American Chemical Society, , vol. 63, p. 774,776 Journal of the American Chemical Society, , vol. 69, p. 2167,2172

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H351-H360
Precautionary Statements : P280-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   4.5153
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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